Quarterly report pursuant to Section 13 or 15(d)

6. Research and Development (Details Narrative)

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6. Research and Development (Details Narrative) - USD ($)
3 Months Ended 6 Months Ended
Jun. 30, 2018
Jun. 30, 2017
Jun. 30, 2018
Jun. 30, 2017
Dec. 31, 2017
Research and Development Arrangement, Contract to Perform for Others [Line Items]          
Research and development expenses $ 48,000 $ 56,000 $ 95,000 $ 120,000  
Accounts payable - licensing agreement 974,000   974,000   $ 852,000
License revenue generated 0 0 0 50,000  
AOT Prototypes [Member]          
Research and Development Arrangement, Contract to Perform for Others [Line Items]          
Research and development expenses 1,000 9,000 1,000 26,000  
Temple University License Agreements [Member]          
Research and Development Arrangement, Contract to Perform for Others [Line Items]          
Research and development expenses 47,000 $ 47,000 94,000 96,000  
Accounts payable - licensing agreement 964,000   964,000   842,000
License revenue generated     0 50,000  
Temple University License Agreements [Member] | Penalty Interest [Member]          
Research and Development Arrangement, Contract to Perform for Others [Line Items]          
Research and development expenses     16,000 $ 20,000  
Temple University License Agreements [Member] | Accounts payable current [Member]          
Research and Development Arrangement, Contract to Perform for Others [Line Items]          
Accounts payable - licensing agreement 68,000   68,000    
Temple University License Agreements [Member] | Accounts payable deferred [Member]          
Research and Development Arrangement, Contract to Perform for Others [Line Items]          
Accounts payable - licensing agreement 405,000   405,000    
Temple University License Agreements [Member] | Accounts payable past due [Member]          
Research and Development Arrangement, Contract to Perform for Others [Line Items]          
Accounts payable - licensing agreement 491,000   491,000    
Temple University Sponsored Research Agreement [Member]          
Research and Development Arrangement, Contract to Perform for Others [Line Items]          
Accounts payable - licensing agreement 10,000   10,000   $ 10,000
Temple University Sponsored Research Agreement [Member] | Accounts payable past due [Member]          
Research and Development Arrangement, Contract to Perform for Others [Line Items]          
Accounts payable - licensing agreement $ 10,000   $ 10,000