Annual report pursuant to Section 13 and 15(d)

2. Summary of Significant Accounting Policies (Details Narrative)

v3.3.1.900
2. Summary of Significant Accounting Policies (Details Narrative) - USD ($)
3 Months Ended 12 Months Ended
Dec. 31, 2015
Sep. 30, 2015
Jun. 30, 2015
Mar. 31, 2015
Dec. 31, 2014
Sep. 30, 2014
Jun. 30, 2014
Mar. 31, 2014
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Dec. 31, 2012
Net loss $ (685,876) $ (825,797) $ (1,542,944) $ (1,174,337) $ (878,695) $ (715,774) $ (1,008,392) $ (1,403,474) $ (4,228,954) $ (4,006,335) $ (10,657,009)  
Cash flow from operations                 (2,595,457) (3,527,695) (5,912,368)  
Stockholders' equity (deficiency) (782,220)       1,368,412       (782,220) 1,368,412 3,075,316 $ (2,897,520)
Cash on Hand $ 349,186       $ 2,247,557       349,186 2,247,557 4,137,068 $ 1,601,791
Impairment on long-lived assets                 0 0 0  
Research and development expenses                 577,501 893,452 2,011,486  
Patent costs                 $ 53,044 $ 103,434 $ 144,326  
Options [Member]                        
Antidilutive shares excluded from loss per share                 21,535,148 21,052,030 20,309,908  
Warrants [Member]                        
Antidilutive shares excluded from loss per share                 4,411,667 5,692,087 11,763,966  
Convertible Notes [Member]                        
Antidilutive shares excluded from loss per share                 509,667 0 0